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Picamilon is regarded as one of the best anxiolytics given that it is a combination of GABA and niacin and can cross the blood-brain barrier easily. It was created in the late 1960s in Russia and is utilized as a prescription drug in Russia, whileas in the United States, it is unregulated.
With niacin as its precursor, Picamilon has the ability to increase energy levels, making it a very unique anxiolytic. Overall it provides a mild tranquilizing effect which helps reduces aggressiveness while being mildly stimulating which can help improve alertness and cognitive function. Picamilon is categorized under GABAergics. It is also known as nicotinoyl-GABA, Pycamilon, Pikamilon.
Picamilon shows antidepressant effect, decreases stress and anxiety, improves memory, learning capacity, focus and attention, relieves migraine and other types of headaches.