PICAMILON


PICAMILON, instructions for use

BUY PICAMILON

International Nonproprietary Name:

nicotinoyl gamma-aminobutyric acid

Dosage form:

pills

Composition:

active substance - nicotinoyl gamma-aminobutyrate sodium - 20 mg or 50 mg,

auxiliary substances - potato starch, magnesium hydroxycarbonate, sugar, calcium stearate, talc.

Description:

tablets of white color, flat-cylindrical with a facet and a risk.

Pharmacotherapeutic group:

nootropic agent.

ATX code [N06BX].


Pharmacological properties

Pharmacodynamics.

Nootropic agent, dilates the vessels of the brain. It also has a tranquilizing, psychostimulating, antiaggregant and antioxidant effect. Improves the functional state of the brain due to the normalization of tissue metabolism and effects on cerebral circulation (increases the volume and linear speed of cerebral blood flow, reduces the resistance of cerebral vessels, inhibits platelet aggregation, improves microcirculation).

At the course reception increases physical and mental efficiency, reduces headache, improves memory, normalizes sleep; contributes to the reduction or disappearance of feelings of anxiety, tension, fear; improves the condition of patients with motor and speech disorders, reduces the inhibitory effect of ethanol on the central nervous system. Improves blood circulation in the vessels of the retina and optic nerve.

Pharmacokinetics.

Absorption is fast and complete. It penetrates the blood-brain barrier, it is retained for a long time in the tissues of the body. Bioavailability is 50-88%. It is excreted mainly by the kidneys in unchanged form. Half-life is 0.51 hours.

Indications for use

Complex therapy of ischemic disorders of cerebral circulation of mild and moderate severity, chronic cerebrovascular insufficiency, states after craniocerebral trauma, treatment of chronic alcoholism (for the reduction of asthenic, asthenoneurotic, postpsychotic, pre-regressive conditions, and alcoholic encephalopathy).

As part of complex therapy for the prevention of migraine. In the complex therapy of primary open-angle glaucoma with compensated pressure, with retinal and optic nerve diseases of vascular origin. In urological practice (in children older than 3 years and in adults with disorders of urination) to improve the adaptive function of the bladder (reducing detoxification hypoxia).

In the complex therapy of the syndrome of vegetative dystonia, accompanied by anxiety, fear, increased irritability, emotional lability.

Contraindications

Hypersensitivity, chronic renal failure, pregnancy and lactation, children under 3 years.Dosing and Administration

Inside, regardless of food intake. With cerebrovascular diseases, a single dose of 0.02-0.05 g 2-3 times a day, a daily dose of 0.06-0.15 g. The course of treatment - 1-2 months. Repeated course - after 5-6 months. For the prevention of migraine attacks, 0.05 g 3 times a day, to stop the attack -0.1 g once.

Depressive states of late age - 0.04-0.2 g / day for 2-3 doses, the optimal dosage is 0.06-0.12 g / day, for 1.5-3 months.

As an anti-asthenic and anxiolytic agent - 0,04-0,08 g / day. if necessary, to 0.2-0.3 g / day, for 1-1.5 months.

At alcoholism during the period of abstinence - 0,1 -0,2 g / day, short course 6-7 days; with more persistent violations outside of abstinence - a daily dose of 0.04-0.06 g for 4-5 weeks.

To restore efficiency and with increased loads - 0,06-0,08 g / day for 1-1,5 months, for athletes in the same dose, during 2 weeks of training period.

At the primary open-eye glaucoma - 0.05 g 3 times a day, for 1 month. For diseases of the retina and optic nerve, the first 12 days of picamilon are injected intramuscularly, then inside by 0.02-0.05 g 3 times a day at a daily dose of 0.06-0.015 g for 1 month.

With disorders of urination: 0.02 g 2-3 times a day (for children from 3 to 10 years); 0.05 g 2 times a day (for children from 11 to 15 years), 0.05 g 3 times a day (for patients older than 15 years). The course of treatment is 1 month.

Side effects

Allergic reactions (skin rash, itching), dizziness, headache, mild nausea. irritability, anxiety, excitement.

Overdose

Increased severity of symptoms of side effects. Treatment is symptomatic.

Interaction with other drugs.

Shortens the time of action of barbiturates, enhances the action of opioid analgesics.

Form of issue

Tablets of 20 mg or 50 mg. 30 tablets in a polymer bank. Bank with instructions for use in a pack of cardboard.

Shelf life

3 years. Do not use after the time specified on the package.

Storage conditions

List B In a dry, dark place, out of the reach of children, at a temperature of no higher than 25 °C

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