Buy Levitra 20 mg 4 tablets

      Active ingredient: Vardenafil

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Levitra is used to treat adult men (aged 18 years or over) with erectile dysfunction (sometimes called impotence), when they cannot get or keep a hard penis (erection) sufficient for satisfactory sexual activity. For Levitra to be effective, sexual stimulation is required.

Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5), the most abundant phosphodiesterase (PDE) isoenzyme in the human penile corpus cavernosum. PDE5 is responsible for the degradation of cGMP in the corpus cavernosum. By inhibiting PDE5, the enzyme responsible for cGMP degradation in the corpus cavernosum, vardenafil enhances the effect of endogenous nitric oxide (NO), locally released in corpus cavernosum upon sexual stimulation. The inhibition of PDE5 by vardenafil leads to increased cGMP levels in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Because sexual stimulation is required to initiate the local release of nitric oxide, the inhibition of PDE5 has little effect in the absence of sexual stimulation. LEVITRA thus potentiates the natural response to sexual stimulation.

After oral administration, Vardenafil is rapidly absorbed and begins to act in 15 minutes (in most men after 25 minutes), the duration of action is 4-5 hours

Contraindications

  • simultaneous therapy with nitrates or drugs that are donors of nitric oxide;
  • combination with HIV protease inhibitors such as indinavir or ritonavir;
  • hypersensitivity to the components of the drug.

The drug is not intended for use in children and adolescents under the age of 16 years.

It should be used with caution in patients with congenital prolongation of the QT interval, with anatomical deformity of the penis (curvature, cavernous fibrosis, Peyronie's disease), with diseases predisposing to priapism (sickle cell anemia, multiple myeloma, leukemia), severe liver dysfunction, end-stage renal disease, arterial hypotension (systolic pressure at rest less than 90 mm Hg), recent stroke and myocardial infarction, unstable angina pectoris, hereditary degenerative diseases of the retina (eg, retinitis pigmentosa), with a tendency to bleeding and with exacerbation peptic ulcer disease, aortic stenosis and idiopathic hypertrophic subaortic stenosis.


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LEVITRA 20mg 4 tablets

  • Product Code: LA20X4
  • Availability: In Stock
  • $89.96

  • Ex Tax: $89.96