Buy Seretide inhaler 25mcg/125mcg 120 doses
Active ingredient: Salmeterol / Fluticasone
Free Shipping
Without prescription
1 inhaler x 120 doses
Short description
Seretide (salmeterol + fluticasone) is an
anti-inflammatory and bronchodilator for use in pulmonary practice. The
pharmacological effect of the medicinal product is determined by the active
ingredients included in its composition, which have different directions of action.
Salmeterol relieves bronchospastic symptoms. Fluticasone normalizes lung
function and prevents the transition of the disease to the acute phase. The
drug has a convenient way of dosing, which makes it an excellent alternative
for patients who are forced to use inhalation monopreparations of the group of
agonists of beta-2-adrenergic receptors and inhaled glucocorticosteroids from
different vials. Salmeterol is a selective agonist of beta-2 adrenoreceptors of
prolonged (up to 12 hours) action. Its pharmacological properties favorably
distinguish it among short-acting beta-2-adrenoreceptor agonists: it more
effectively protects against narrowing of the lumen of the bronchi provoked by
histamine and provides a longer bronchodilator effect. Studies of salmeterol
showed that this substance is capable of significantly suppressing the release
of mediators of allergic reactions by the lung cells (histamine, leukotrienes,
etc.). The substance inhibits the initial and late phases of the immune
response to the effects of allergenic substances that enter the body through
the respiratory tract. The suppression of the late phase of the immune response
after using a single dose of the drug lasts more than a day, while the
bronchodilator effect ceases. A single use of salmeterol reduces bronchial
hypersensitivity. This suggests the presence of another mechanism of action, in
addition to bronchodilating activity, the clinical significance of which has
not yet been definitively determined.
The anti-inflammatory effect of
glucocorticosteroids is based on a different path. Fluticasone is a local
glucocorticosteroid that, when administered through the respiratory tract in
the doses indicated in the package leaflet, has a powerful anti-inflammatory
and antiallergic effect in the respiratory organs, which minimizes the risk of
asthma passing into the acute phase. It is important that this active
ingredient Seretid does not provoke undesirable side effects that occur when
using glucocorticosteroids for systemic (oral, injectable) use. With prolonged
use of fluticasone (including in submaximal and maximum dosages), the work of
the adrenal cortex is not suppressed and remains within the physiological
limits of patients of all age groups. After the withdrawal of other inhaled glucocorticosteroids
and the appointment of fluticasone in patients, the secretory activity of the
adrenal cortex gradually returns to normal. Fluticasone does not impair the
reserve function of the adrenal cortex, as evidenced by a moderate increase in
cortisol with appropriate stimulation. Before starting treatment, the patient
should be informed that the optimal effect can be achieved only with regular
use of Seretide. The drug should continue to be taken even after the
disappearance of the signs of existing pulmonary pathology. Termination of
admission is possible only in consultation with the doctor. During treatment,
regular medical monitoring should be conducted to evaluate the effectiveness of
drug therapy. The question of the duration of receiving Seretid and the
possibility of adjusting its dose is decided by the doctor individually. In
pediatric practice, the drug is used when the patient reaches four years of
age.
Many people want to buy Seretide for its excellent properties. Seretide contains two medicines: salmeterol and fluticasone propionate. Salmeterol is a long-acting bronchodilator. Bronchodilators help the airways in the lungs to stay open. This makes it easier for air to get in and out. The effects last for at least 12 hours. Fluticasone propionate is a corticosteroid which reduces swelling and irritation in the lungs.
Seretide
side effects
Since
Seretid contains salmeterol and fluticasone propionate, its side effects are
characteristic of each of these drugs. Their simultaneous use does not cause
additional side effects.
Seretide
may cause paradoxical bronchospasm.
As
part of clinical studies using Seretid, there have sometimes been reports of
bruising, as well as frequent cases of pneumonia (in patients with COPD).
As
part of post-marketing surveillance, the following data on adverse events was
obtained.
Seretide
Sometimes
hypersensitivity reactions have been reported, incl. manifested as skin
reactions, angioedema (mainly edema of the face and oropharynx), respiratory
disorders (shortness of breath and / or bronchospasm), and in very rare cases -
anaphylactic reactions.
Anxiety,
behavioral disorders (including hyperactivity and irritability, mainly in
children), sleep disorders, and hyperglycemia were also very rarely observed.
Salmeterol
On
the part of the cardiovascular system: palpitations, headache (usually
transient, decrease with the continuation of therapy salmeterol); in predisposed
patients, cardiac arrhythmias are possible (including atrial fibrillation,
supraventricular tachycardia, extrasystole).
On
the part of the digestive system: rarely - abdominal pain, nausea, vomiting; in
some cases - a violation of taste, irritation of the mucous membranes of the
oropharynx.
Allergic
reactions: rash, angioedema, local edema.
Other:
tremor, hypokalemia (as a rule, transient, decrease with the continuation of
therapy salmeterol); rarely - arthralgia, nervousness; very rarely - hyperglycemia;
in some cases, painful muscle spasms.
Fluticasone
Propionate
On
the part of the respiratory system: hoarseness, candidiasis of the oral cavity
and pharynx.
Allergic
reactions: skin manifestations, angioedema (mainly of the face and oropharynx),
respiratory symptoms (shortness of breath and / or bronchospasm), anaphylactic
reactions.
Systemic
reactions: it is theoretically possible to develop systemic reactions,
including Cushing's syndrome, cushingoid symptoms, adrenal suppression, growth
retardation in children and adolescents, reduced bone mineral density,
cataracts and glaucoma.
Anxiety,
sleep disorders and behavioral disorders, including hyperactivity and
irritability (mainly in children), hyperglycemia have been reported very
rarely.
Contraindications
-
children's age up to 4 years;
-
hypersensitivity to the drug.
Seretide
should be prescribed with caution in case of pulmonary tuberculosis, fungal,
viral or bacterial infections of the respiratory system, thyroxomycosis,
diabetes mellitus, diabetes mellitus, uncontrolled hypokalemia, idiopathic
hypertrophic subaortic stenosis, uncontrolled arterial hypertension,
arrhythmias, or untreated hypertrophic subaortic stenosis, uncontrolled
arterial hypertension, arrhythmias, or untreated hypertrophic subaortic
stenosis, uncontrolled arterial hypertension, arrhythmias, or untreated
hypertrophic subaortic stenosis; , cataract, glaucoma, hypothyroidism,
osteoporosis, pregnancy, in the period of lactation.
Seretide for sale: No prescription is required, but a valid prescription or doctor's recommendation is assumed. Please don't heal yourself. Get expert advice before buying Seretide online.
The drug images are only for illustration purposes and may not exactly represent real product. This product is for the Russian market and can be labeled in Russian (package design may vary). To make sure you're buying the right product, use Google Translate to translate the word Серетид into English. Just copy and paste.
SERETIDE 25/125mcg INHALER 120 doses
- Product Code: SD25/125
- Availability: In Stock
-
$44.96
- Ex Tax: $44.96