Buy Afobazol (Afobazole) 10mg 60 tablets
Active ingredient: Fabomotizole
1 box x 60 tablets
Afobazole, also known as afobazol, is a nootropic medication that is mostly used to treat disorders related to stress and anxiety. The medication reduces anxiety symptoms and encourages relaxation by altering brain levels of certain neurotransmitters. Afobazol is usually taken in the morning or as directed by a medical professional at a dosage of 10-20 mg per day.
Afobazole can be used to treat a number of conditions, including panic disorder, generalized anxiety disorder, and obsessive-compulsive disorder. Additionally, it is used to boost motivation, reduce fatigue, and improve cognitive function in individuals with depression and other mood disorders.
Afobazole, on the other hand, has contraindications and side effects just like any other medication. People with severe liver or kidney disease, as well as women who are pregnant or breastfeeding, should not take the medication. Afobazole side effects include drowsiness, headache, nausea, and dizziness.
Afobazole can be purchased online from a variety of pharmacies and websites; however, it is essential to verify that the source is reputable and licensed. It is best to discuss any potential risks and benefits with a healthcare professional prior to taking any new medication to determine if it is safe and suitable for you.
In conclusion, it has been demonstrated that afobazole, a nootropic medication, is effective in treating disorders related to stress and anxiety. Before beginning treatment, it is critical to be aware of its contraindications and side effects, despite the fact that it has a number of advantages.
Afobazol is the new generation drug, a synthetic anxiolytic, it effectively restores the anti-stress resources of the human body, so it does not cause addiction and addiction in patients. In comparison with many sedative and anticonvulsants, Afobazol does not adversely affect physical activity and does not suppress the activity of the nervous system. After its administration, there are no side effects such as weakness, drowsiness, memory loss, absent-mindedness. In addition, Afobazol successfully copes not only with the psychological manifestations of stress and anxiety, but also eliminates physical disorders associated with the development of mental disorders.
Afobazole is a selective anxiolytic according to its mechanism of action: the drug counteracts the development of membrane-dependent changes in gamma-aminobutyric acid receptors (GABA is the main inhibitory neurotransmitter). It does not have a sedative effect (unless, of course, do not exceed the recommended dose ten times). The pharmacological effect of Afobazole is a combination of an anti-anxiety and a light activating component.
Already on the 5-7th day of taking Afobazol, a decrease or complete elimination of anxiety, irritability, anxious forebodings, tearfulness, phobias, and inability to relax is noted. Against this background, the combined somatic symptoms begin to disappear: muscle, cardiovascular, sensory, respiratory and digestive manifestations of pathological anxiety. The peak action of afobazole occurs at the end of the 4th week and persists for another 1-2 weeks after discontinuation of the drug.
Many people want to buy Afobazol(e) for its excellent properties. Afobazole has anxiolytic effect and used in anxiety conditions, including burdened with somatic symptoms. To suppress such conditions, medicine may propose, for example, benzodiazepine tranquilizers or antidepressants. The problem is that these groups of drugs, in addition to the undeniable advantages, are endowed with a number of disadvantages.
A reasonable alternative to eliminate pathological anxiety may be Afobazole. Its use is not associated with adverse reactions characteristic of the benzodiazepine tranquilizers - lethargy, drowsiness, muscle relaxation, impaired coordination of movement, which can impair the quality of life. At the same time, Afobazol has several advantages: low toxicity, the ability to use in complex therapy without increasing the risk of adverse reactions, low risk of addiction and withdrawal. Thus, the drug in its anxiolytic properties practically corresponds to benzodiazepines and is suitable for long-term pharmacotherapy, as devoid of side effects characteristic of tranquilizers.
Afobazole® is a selective non-benzodiazepine anxiolytic. Acting on sigma-1 receptors in brain nerve cells, Afobazole® stabilizes GABA / benzodiazepine receptors and restores their sensitivity to endogenous inhibitory mediators. Afobazole® also increases the bioenergetic potential of nerve cells and protects them from damage (it has a neuroprotective effect).
The action of the drug is implemented mainly in the form of a combination of anxiolytic (anti-anxiety) and mild stimulating (activating) effects. Afobazol® reduces or eliminates anxiety (preoccupation, bad feelings, apprehension, irritability), tension (timidity, tearfulness, anxiety, inability to relax, insomnia, fear), somatic manifestations of anxiety (muscle, sensory, cardiovascular, respiratory, gastrointestinal -intestinal symptoms), autonomic disorders (dry mouth, sweating, dizziness), cognitive impairment (difficulty concentrating, impaired memory). Especially shown is the use of the drug in individuals with predominantly asthenic personality traits in the form of anxious suspiciousness, uncertainty, increased vulnerability and emotional lability, a tendency to emotional-stress reactions. The effect of the drug develops on the 5-7th day of treatment. The maximum effect is achieved by the end of 4 weeks of treatment and persists after an average of 1-2 weeks after treatment. Afobazol® does not cause muscle weakness, drowsiness and does not have a negative effect on concentration and memory. With its use, drug dependence is not formed and the “withdrawal" syndrome does not develop.
After oral administration, Afobazole® is well and rapidly absorbed from the gastrointestinal tract. Cmax - 0.130 + 0.073 μg / ml; TCmax - 0.85 ± 0.13 h.
Afobazole® undergoes a “first pass effect” through the liver, the main areas of metabolism are hydroxylation along the aromatic ring of the benzimidazole ring and oxidation along the morpholine fragment. Afobazole® is intensively distributed over well-vascularized organs; it is characterized by a rapid transfer from the central pool (blood plasma) to the peripheral (highly vascularized organs and tissues).
The half-life of Afobazole® when taken orally is 0.82 + 0.54 hours. The short half-life is due to the intense biotransformation of the drug and the rapid distribution from the blood plasma to organs and tissues. The drug is excreted mainly in the form of metabolites and partially unchanged with urine and feces.
With prolonged use, it does not cumulate in the body.
It is applied inside, after food.
The optimal single dose is 10 mg; daily allowance - 30 mg, distributed in 3 doses throughout the day, The duration of the course of the drug is 2-4 weeks. If necessary, on the recommendation of a doctor, the daily dose of the drug can be increased to 60 mg, and the duration of treatment up to 3 months.
With a significant overdose and intoxication, the development of a sedative effect and increased drowsiness without manifestations of muscle relaxation is possible. As an emergency, caffeine 20% solution in ampoules of 1.0 ml 2-3 times a day subcutaneously is used.
Allergic reactions are possible. Rarely, a headache that usually resolves on its own and does not require withdrawal the drug
Afobazole® is used in adults with anxiety conditions:
· generalized anxiety disorders;
· adaptation disorders.
In patients with various somatic diseases:
· bronchial asthma;
· irritable bowel syndrome;
· systemic lupus erythematosus;
· cardiac ischemia;
· hypertonic disease;
· dermatological, oncological and other diseases.
In the treatment of:
· sleep disturbances associated with anxiety;
· neurocirculatory dystonia;
· premenstrual syndrome;
· alcohol withdrawal syndrome;
· to alleviate the "withdrawal" syndrome when quitting smoking.
· individual intolerance to the drug.
· galactose intolerance, lactase deficiency or glucose-galactose malabsorption;
· pregnancy, lactation;
· children, under 18 years old.
Afobazol for sale: No prescription is required, but a valid prescription or doctor's recommendation is assumed. Please don't heal yourself. Get expert advice before buying Afobazole online.
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AFOBAZOL 10mg 60 tablets
- Product Code: AF10X60
- Availability: In Stock
- Ex Tax: $31.98