• METFORMIN (Generic Glucophage) 500mg 60 tablets

Buy Metformin 500mg 60 tablets

Active ingredient: metformin hydrochloride

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Metformin, a medication also referred to as its branded name Glucophage, is an oral hypoglycemic agent commonly utilized in the treatment of type 2 diabetes mellitus. The starting dose of Metformin is typically 500 mg once or twice a day, and the maximum daily dose of 2550 mg can be gradually achieved as tolerated. The dosage of Metformin is frequently adjusted based on the patient's blood glucose levels and kidney function.

Metformin is indicated for the management of type 2 diabetes mellitus and is specifically beneficial for patients who are overweight, as it can aid in the improvement of insulin resistance and reduction of blood glucose levels. However, severe kidney disease or liver dysfunction contraindicate the use of Metformin due to an increased risk of lactic acidosis, a rare but potentially life-threatening adverse effect of Metformin.

Despite its generally favorable tolerability, Metformin may result in various side effects, such as nausea, diarrhea, abdominal discomfort, and flatulence. Such symptoms can often be managed by reducing the dose of Metformin or taking it with food. In rare cases, Metformin can also elicit severe adverse effects such as lactic acidosis, a condition characterized by high levels of lactic acid in the blood, which can lead to organ damage and even death.

A prescription drug called metformin is available from a number of places, including neighborhood pharmacies and online merchants. When using Metformin, it's critical to strictly adhere to the recommended dosage and instructions to maximize its effectiveness and lower the chance of side effects. Before taking Metformin, as with any drug, it's crucial to talk to your doctor. You should also let them know if you experience any strange symptoms or adverse effects.

Short description

At the present time, without exaggeration, metformin is the most frequently prescribed tablets of hypoglycemic agents. Metformin inhibits the process of gluconeogenesis (glucose synthesis) in the liver, reduces the absorption of glucose in the small intestine, increases the ability of peripheral tissues to utilize glucose, increases the receptor sensitivity of tissues to insulin. Most importantly, the drug does not affect the production of insulin by the pancreas and does not cause hypoglycemic reactions characteristic of some sugar-reducing agents (which may be of extreme hypoglycemic coma).

Among other pharmacological effects of the drug, mention should be made of reducing the concentration of triglycerides and "bad" lipoproteins (LDL) in the blood, stabilizing (and in some cases even reducing) the patient's own weight, fibrinolytic (antithrombotic) action.

The dose of metformin is determined by the doctor in each particular case and depends on the initial level of glucose in the blood of diabetes patients. According to the general recommendations, the drug is started from 500-1000 mg (which is equivalent to 1-2 tablets). After 10-14 days it is allowed to increase the dose, based on current indicators of its concentration in the blood. Maintenance dose of metformin ranges from 1500-2000 mg, the maximum is 3000 mg.

It should be noted that for patients over 60 years old who continue to engage in heavy physical labor, metformin can cause lactic acidosis. In this regard, taking the drug in these patients is contraindicated. In other cases, the elderly should take no more than 1000 mg of metformin per day. Tablets are recommended to be taken during food or immediately after it, washing down with a glass of water. The daily dose is usually divided into 2-3 doses.

 Many people want to buy Metformin for its excellent properties. Metformin inhibits gluconeogenesis in the liver, reduces the absorption of glucose from the intestine, increases peripheral glucose utilization, and also increases the sensitivity of tissues to insulin. It does not affect insulin secretion by pancreatic beta cells, does not cause hypoglycemic reactions. It lowers triglycerides and low density lipoproteins in the blood. Mtnformin helps in weight loss. It has a fibrinolytic effect by suppressing a tissue-type plasminogen activator inhibitor. 

Metformin is widely used for PCOS treatment:

80% of women with polycystic ovaries on monotherapy with metformin or one of the glitazones spontaneously restored ovulation, normalized menstrual cycle, decreased androgen secretion by the ovaries and disappeared or decreased hyperandrogenic symptoms, decreased body weight, normalized carbohydrate metabolism, improved mental state. Most of these women were then able to bear and give birth to healthy children.

Side effects

On the part of the digestive system: possible (usually at the beginning of treatment) nausea, vomiting, diarrhea, flatulence, feeling of discomfort in the abdomen; in rare cases - violation of liver function indicators, hepatitis (disappear after stopping treatment).

Metabolism: very rarely - lactacidosis (discontinuation of treatment is required).

On the part of the blood system: very rarely - a violation of the absorption of vitamin B12.

The profile of adverse reactions in children aged 10 years and older is the same as in adults.


Acute or chronic metabolic acidosis, diabetic ketoacidosis, diabetic precoma and coma; renal failure, impaired renal function (CC <60 ml / min); dehydration, severe infection, hypoglycemic shock, which can lead to impaired renal function; clinically pronounced symptoms of acute and chronic diseases that can lead to the development of tissue hypoxia (including heart failure, acute myocardial infarction, respiratory failure); the use of contrast iodine-containing substances for intravascular administration (including during intravenous urography, intravenous cholangiography, angiography, CT); acute alcohol intoxication, chronic alcoholism; hypersensitivity to metformin.

Metformin for sale: No prescription is required, but a valid prescription or doctor's recommendation is assumed. Please don't heal yourself. Get expert advice before buying Metformin online.

The drug images are only for illustration purposes and may not exactly represent real product. This product is for the Russian market and can be labeled in Russian (package design may vary). To make sure you're buying the right product, use Google Translate to translate the word Метформин into English. Just copy and paste.

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METFORMIN (Generic Glucophage) 500mg 60 tablets

  • Product Code: MF500X60
  • Availability: In Stock
  • $22.82

  • Ex Tax: $22.82