Buy Metformin (generic Glucophage) 500mg 60 tablets
Active ingredient: metformin hydrochloride
1 box x 60 tablets x 500mg [also available 850mg and 1000mg]
At the present time, without exaggeration, metformin is the most frequently prescribed tablets of hypoglycemic agents. Metformin inhibits the process of gluconeogenesis (glucose synthesis) in the liver, reduces the absorption of glucose in the small intestine, increases the ability of peripheral tissues to utilize glucose, increases the receptor sensitivity of tissues to insulin. Most importantly, the drug does not affect the production of insulin by the pancreas and does not cause hypoglycemic reactions characteristic of some sugar-reducing agents (which may be of extreme hypoglycemic coma).
Among other pharmacological effects of the drug, mention should be made of reducing the concentration of triglycerides and "bad" lipoproteins (LDL) in the blood, stabilizing (and in some cases even reducing) the patient's own weight, fibrinolytic (antithrombotic) action.
The dose of metformin is determined by the doctor in each particular case and depends on the initial level of glucose in the blood of diabetes patients. According to the general recommendations, the drug is started from 500-1000 mg (which is equivalent to 1-2 tablets). After 10-14 days it is allowed to increase the dose, based on current indicators of its concentration in the blood. Maintenance dose of metformin ranges from 1500-2000 mg, the maximum is 3000 mg.
It should be noted that for patients over 60 years old who continue to engage in heavy physical labor, metformin can cause lactic acidosis. In this regard, taking the drug in these patients is contraindicated. In other cases, the elderly should take no more than 1000 mg of metformin per day. Tablets are recommended to be taken during food or immediately after it, washing down with a glass of water. The daily dose is usually divided into 2-3 doses.
Metformin is widely used for PCOS treatment:
80% of women with polycystic ovaries on monotherapy with metformin or one of the glitazones spontaneously restored ovulation, normalized menstrual cycle, decreased androgen secretion by the ovaries and disappeared or decreased hyperandrogenic symptoms, decreased body weight, normalized carbohydrate metabolism, improved mental state. Most of these women were then able to bear and give birth to healthy children.
On the part of the digestive system: possible (usually at the beginning of treatment) nausea, vomiting, diarrhea, flatulence, feeling of discomfort in the abdomen; in rare cases - violation of liver function indicators, hepatitis (disappear after stopping treatment).
Metabolism: very rarely - lactacidosis (discontinuation of treatment is required).
On the part of the blood system: very rarely - a violation of the absorption of vitamin B12.
The profile of adverse reactions in children aged 10 years and older is the same as in adults.
Acute or chronic metabolic acidosis, diabetic ketoacidosis, diabetic precoma and coma; renal failure, impaired renal function (CC <60 ml / min); dehydration, severe infection, hypoglycemic shock, which can lead to impaired renal function; clinically pronounced symptoms of acute and chronic diseases that can lead to the development of tissue hypoxia (including heart failure, acute myocardial infarction, respiratory failure); the use of contrast iodine-containing substances for intravascular administration (including during intravenous urography, intravenous cholangiography, angiography, CT); acute alcohol intoxication, chronic alcoholism; hypersensitivity to metformin.
Metformin for sale: Even if a prescription is not required, it is assumed that you have a valid prescription or doctor's recommendation. Please do not self-cure. Get expert advice before ordering.
The product is intended for Russian market and can be labeled in Russian (Packaging design may vary). With detailed English printed manual.